Greenup moved to Frankfort in 1792.  He served in
the U.S. House of Representatives, the Kentucky
House, served as clerk of the Senate and was a
candidate for governor in 1800.  Two years later he
was appointed to the circuit court. In 1804 he resigned
to become a candidate for the governorship of Kentucky,
were he ran unopposed.  During his administration the
state purchased stock in the Ohio Canal Company and
the Bank of Kentucky.  Greenup was unsuccessful in
his fight for state provided public education. He left office
on September 1, 1808 and was one of the most esteemed
governors of that day. Christopher Greenup died at his
residence in Frankfort, Kentucky on April 17, 1818
and is buried in the Frankfort Cemetery, section M.

The monument that marks the grave of Governor Madison
and Governor Greenup was erected by resolution of the
Legislature in 1874.

Update!  - April 1, 2011
Elise Greenup Jourdan has submitted the following:
Contrary to most published information, Greenup was born
in Maryland.  At age ca. 9 when his brother John sold the
family farm in what is now Frederick County, Maryland, he
appeared at the home of Col. Binns in Loudon County, Virginia.
I have spent 40 years researching the records of Maryland
and Virginia and there was no Greenup in Virginia prior to the
later part of the 1700's.  I do not think it is possible to ever
get this corrected, but I will be glad to detail my evidence of
his birth in Maryland.